Rytis Prekeris Lab
University of Colorado Anschutz Medical Campus
2021
Gibieza, P., Peterman, E., Hoffman, H.K., Van Engeleburg, S., Skeberdis, V.A., and Prekeris, R. (2021) Rab14/MACF2 complex regulates endosomal targeting during cytokinesis. Molecular Biology of the Cell. In Press.
Jewett, C.E., Soh, A.W.J., Lin, C.H., Lencer, E., Westlake, C.J., Pearson, C.G., and Prekeris, R. (2021) Rab19 directs cortical remodeling and membrane growth for primary ciliogenesis. Developmental Cell. 56(3):325-340.
Linklater, E.S., Duncan, E.D., Han, K.J., Kaupinis, A., Valius, M., Lyons, T.R. and Prekeris, R. (2021) Rab40/Cullin5 complex regulate EPLIN and actin cytoskeleton dynamics during cell migration and invasion. Journal of Cell Biology. In Press.
2020
Peterman, E., Valius, M., and Prekeris, R. (2020) CLICK4 is a cytokinesis cleavage furrow protein that regulates cortical cytoskeleton stability during cell division. Journal of Cell Science. 133(9). PMID: 32184265.
Jewett, C.E., Appel, B.H., and Prekeris, R. (2020) The Rab11 effectors Fip5 and Fip1 regulate zebrafish intestinal development. Biology Open. In Press.
2019
Peterman, E., Gibieza, P., Schafer, J., Skeberdis, A., Kaupinis, A., Valius, M., Heiligenstein, X., Hurbain, I., Raposo, G., and Prekeris, R. (2019) The Post-Abscission Midbody is an Intracellular Signaling Organelle that Regulates Cell Proliferation. Nature Communications. 18;10(1):318. PMID: 31320617
Peterman, E., and Prekeris, R. (2019) The post mitotic midbody: Regulating polarity, stemless, and proliferation. Journal of Cell Biology. 218(12):3903-3911. PMID: 31690620
2018
Jewett, C. and Prekeris, R. (2018) Insane in the apical membrane: trafficking events mediating apicobasal epithelial polarity during tube morphogenesis. Traffic. PMID: 29766620.
Gibieza, P. and Prekeris, R. (2018) Rab GTPases and cell division. Small GTPases. In Press. PMID: 28471300.
2017
Peterman, E., and Prekeris, R. (2017) Understanding post-mitotic roles of the midbody durtting cell differentiation and polarization. Methods in Cell Biology. 237:173-186. PMID: 28065304
Linklater, E., Jewett, C., and Prekeris, R. (2017) Polarized membrane trafficking in development and disease: from epithelia polarization to cancer cell invasion. Book "Cell Polarity in Development and Disease". In Press
Gibieza, P., and Prekeris, R. (2017) Rab GTPases and cell division. Small GTPases. In Press
Dionne L.K., Peterman, E., Schiel, J., Gibieza, P., Skeberdis, V.A., Jimeno, A., Wang, X.J., and Prekeris, R. (2017) FYCO1 regulates accumulation of post-mitotic midbodies by mediating LC3-dependent midbody degradation. Journal of Cell Science. In Press
2016
Mangan, A., Sietsema, D.V., Li, Dongying., Moore, J.K., Citi, S., and Prekeris, R. (2016) The role of cingulin and actin in mediating midbody-dependent apical lumen initiation and formation in eoithelial cells. Nature Communications. 7:12426. PMID: 27484926
Jacob, A., Linklater, E., Bayless, B., Lyons, T., and Prekeris, R (2016) The Role and Regulation of Rab40b/Tks5 Complex During Invadopodia Formation and Cancer Cell Invasion. Journal of Cell Science. 129:4341-4353. PMID: 27789576
2015
Mangan, A., and Prekeris, R. (2015) 3D-Time-Lapse analysis of Rab11/FIP5 complex: spatiotemporal dynamics during apical lumen formation. Methods in Molecular Biology. 1298:181-186. PMID: 25800842
Jacob, A., and Prekeris, R. (2015) Regulation of MMP targeting to invadopodia during cancer metastasis. Frontiers in Cell and Developmental Biology. 3:4. PMID: 25699257
Prekeris, R. (2015) Analyzing the functions of Rab11 effector proteins during cell division. Methods in Cell Biology. 1298:181-186. PMID: 26360025
Dionne, L.K., Wang, X.J. and Prekeris, R. (2015) Midbody: From cellular junk to cell polarity and cell fate regulator. Current Opinion in Cell Biology. 35:51-58. PMID: 25950842
Blasky, A., Mangan, A. and Prekeris, R. (2015) Polarized protein transport and lumen formation during epithelial tissue morphogenesis. Annual Review of Cell and Developmental Biology. In Press. PMID: 26359775
2014
Li, D., Mangan, A., Ciccini, L., Margolis, B., and Prekeris, R. (2014) FIP5 phosphorylation during mitosis regulates apical trafficking and luminogenesis. EMBO reports. 15(4):428-437. PMID: 24591568
Li, D., Kuehn, E.W., and Prekeris, R. (2014) Kinesin-2 mediates apical endosome transport during epithelial lumen formation. Cellular Logistics. 4(1):e28928. PMID: 24843830
2013
Jacob, A., Jing, J., Lee, J., Schedin, P., Peden, A.A., Junutula, J.R. and Prekeris, R. (2013) Rab40b regulates MMP2 and MMP9 trafficking during invadopodia formation and breast cancer cell invasion. Journal of Cell Science. 126:4647-4658. PMID: 23902685.
Schiel, J., Childs, C., and Prekeris, R. (2013) Endocytic transport and cytokinesis: from regulation of the cytoskeleton to midbody inheritance. Trends in Cell Biology. 23(7):319-327. PMID: 23522622
2012
Prekeris, R. (2012) Making the final cut: the role of endosomes during mitotic cell division. Chapter in Book “Membrane Trafficking”.
Schiel, J., and Prekeris, R. (2012) Membrane dynamics during cytokinesis. Current Opinion in Cell Biology. 25(1):92-98. PMID: 23177492.
Collins, L.L., Simon, G.S., Matheson, J., Wu, C., Miller, M.C., Otani, T., Yu, X., Prekeris, R., and G.W. Gould (2012) Rab11-FIP3 is a cell cycle-regulated phosphoprotein. BMC Cell Biology. 13(1):4. PMID: 22401586
Schiel, J.A., Simon, G., Castle, D., Christine C.W., D., and Prekeris, R. (2012) FIP3-endosome mediated actin depolymerization and formation of the secondary ingression mediates ESCRT-III recruitment to the abscission site during cytokinesis. Nature Cell Biology. 14(10):1068-1078. PMID: 23000966
2011
Schiel, J., Park, K., Morphew, M.K., Reid, E., Hoenger, A., and Prekeris, R. (2011) Coordinated Endocytic Membrane Fusion and Buckling-Induced Microtubule Severing Mediate Cell Abscission. Journal of Cell Science. 124:1411-1424. PMID: 21486954 37.
Willenborg, C., Jing, J., Wu, C., Matern, H., Burden, J., and Prekeris, R. (2011) FIP5/Rip11 and SNX18 Interaction Regulates Epithelial Lumen Formation. The Journal of Cell Biology. 195(1):71-86. PMID: 21969467.
Willenborg, C., and Prekeris, R. (2011) Apical protein transport and lumen morphogenesis in polarized epithelial cells. Bioscience Reports. 31(4):245-256. PMID: 21366541
Schiel, J., and Prekeris, R. (2011) ESCRT or Endosomes? – Tales of the Separation of Two Daughter Cells. Communicative & Integrative Biology. 4(5):606-608. PMID: 22046476
Prekeris, R. (2011) Actin Regulation During Abscission: Unexpected Roles of Rab35 and Endocytic Transport. Cell Research. 21(9):1283-1285. PMID: 21844893Peterman, E., Gibieza, P., Schafer, J., Skeberdis, A., Kaupinis, A., Valius, M., Heiligenstein, X., Hurbain, I., Raposo, G., and Prekeris, R. (2019) The Post-Abscission Midbody is an Intracellular Signaling Organelle that Regulates Cell Proliferation. Nature Communications. In Press.
